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PLAB04-120

Arlo is 9 months old and seen with his mother who has noticed something unusual when looking through their recent holiday photos. In photos where the flash was used, a red right eye is often seen but never a red left eye. She is concerned about the appearance of the left eye and you suspect that Arlo may have an early retinoblastoma.

Which one of the following features is least likely to be an early feature of retinoblastoma?

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