Mrs Thomas is an 85 year old lady who has metastatic colorectal cancer and is struggling with pain. She has been on Morphine Sulphate modified-release tablets for several months and takes 20mg twice daily. On top of this she requires 5mg of Oramorph on average 8 times a day.

What dose of Morphine Sulphate modified-release tablets should she be up titrated to?


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