You are covering a colleague who is away and receive a result of a patient’s fungal nail scrapings. Looking at the patients notes you see that Mrs Tucker is a 39 year old air-hostess who first presented three months ago with an antalgic gait, secondary to fungal nail infection. She was advised to buy nail lacquer over the counter but symptoms persisted. Eight weeks later, symptoms were progressing so fungal scrapings were sent. Results reveal two positive microscopy and culture samples for non-dermatophytes. Mrs Tucker is normally fit and well and is not on any regular medications. She smokes four cigarettes a week when socialising.
What is the most appropriate first line treatment?